Yes! 20' x 20' installations are common for us and require the purchase of two, three or four 24K BTU air conditioners (each with a CoolBot). The number of A/Cs depends on cooler height, temperature goal, ambient temperature, and volume of product coming in the cooler.
We have done larger installations, up to 60' x 40'. Please call or email us with the details of your cooler and conditions to help determine your cooling requirements. (Cooler Construction Advice Form)